The Cardinals stunned the Canes 24-21 at Hard Rock Stadium, giving both teams 5-1 records. Heisman Trophy favorite Carson Beck threw four interceptions. More: Where will Miami football fall in top 25 after Louisville loss?

The Cardinals are coming off a tough loss, but beat the loaded Hurricanes, and everything changes. Here’s the Miami vs Louisville preview and prediction.

The Cardinals jumped out to a 14-0 lead in the opening quarter and never trailed as Jeff Brohm outcoached Mario Cristobal.

The Miami Hurricanes dropped a close 24-21 game to the Louisville Cardinals on Friday night in Miami that served as a wake-up call for coach Mario Cristobal’s team. The Hurricanes fell to 5-1 on the season while Jeff Brohm’s Cardinals improved their record to the same mark.

The Miami Hurricanes lost their first game of the season on Friday, falling 24-21 to the Louisville Cardinals at Hard Rock Stadium.

Louisville opened with a 75-yard drive capped by quarterback Miller Moss’ short touchdown run — his third straight game finding the end zone on the ground. The Cardinals faked a field goal on fourth-and-2 to extend the drive before Moss scored to make it 7-0.

Carson Beck's Heisman Trophy odds took a major hit Friday night after No. 2 Miami lost 24-21 to the unranked Louisville Cardinals.