Chromatography has long been the workhorse of high-resolution bioseparation. It is the most commonly used technique for preparative work, and is second only to electrophoresis in analysis. Most ...

Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...

Fast protein liquid chromatography (FPLC) is, as the term implies, an effective (fast) liquid chromatography technique for the separation of protein molecules. The term also implies that the mobile ...

Ion exchange chromatography (IEX) is a versatile and widely used technique for separating biomolecules based on charge. It plays a critical role in protein purification in research and ...

Several chromatographic resins are available for downstream purification. Monoclonal antibodies (mAbs) are a successful class of therapeutic products used increasingly in the past 15-20 years, but the ...

In literature, the terms “ion exchange chromatography” and “ion chromatography” (IC) are often used interchangeably, thanks to the wide use of IEX, and refer to the separation of polar or ionic ...

The biopharma industry is looking at continuous chromatography for sensitive molecules. Continuous processes continue to advance in bioprocessing. In downstream processing, continuous chromatography ...

The production of viruses, whether for use as viral vaccines, viral vectors for gene therapy, or oncolytic applications, requires complex processes that can translate into high costs, as well as slow ...

Ion exchange separates components in a sample depending on their relative ionic strengths and interaction with the stationary phase. The stationary phase is a charged substance that selectively ...

There are a variety of uses for affinity chromatography purification techniques. They are being increasingly used to separate pharmaceutical and biological samples nowadays. Here are several ways that ...