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49ers vs. Buccaneers Final Score Prediction for NFL Week 6 (Can San Francisco Pull off Upset?)

Their offense has been good, but their 20th ranking on defense and 31st ranking on special teams hurts them.

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Covers.com · 1d

49ers vs Buccaneers Predictions, Picks & Best Bets for NFL Week 6

NFL Week 6 confidence picks: Dolphins, 49ers, Lions among upset picks

Santa Rosa Press Democrat · 7h

49ers face Buccaneers in matchup of 4-1 teams playing well despite injuries

The San Francisco 49ers and Tampa Bay Buccaneers are winning despite a slew of injuries to key players.

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49ers vs Buccaneers Props & Best Bets for Week 6

Buccaneers vs. 49ers best bets, picks and odds | Week 6 2025

NFL Week 6 same game parlay picks: Buccaneers vs. 49ers 2025

Winning the spread, total and Baker Mayfield over 244.5 passing yards parlay for the Buccaneers-49ers game pays out an estimated $55.35 on a $10 bet using the computer picks below.

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49ers activate two key defensive players for Week 6 road game vs. Buccaneers

Buccaneers vs. 49ers 2025 Prediction, Odds, Picks - Oct 12