Scientists have solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, the major energy source of cells. A team of scientists headed by Rosalind Franklin ...

ATP synthase is a universal molecular machine for energy conversion. By coupling to cellular respiration in mitochondria, it catalyzes conversion of chemical energy of cells. Mitochondrial ATP ...

A team of scientists headed by Rosalind Franklin University Professor David M. Mueller, PhD, has solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, ...

The mitochondrial adenosine triphosphate (ATP) synthase produces most of the ATP required by mammalian cells. We isolated porcine tetrameric ATP synthase and solved its structure at 6.2-angstrom ...

Found inside mitochondria, ATP synthase generates the energy storage molecule adenosine triphosphate, which the cells of all living things use for fuel. The enzyme generally looks similar in shape ...

Figure 1: Structural arrangement of γ′ and ɛ-subunits from E. coli ATP synthase. The γ′–ɛ complex was crystallized from 0.5 M tartrate buffered with 0.1 M Tris-HCl at pH 8.8 (space group C222 1, a = ...

The endogenous inhibitor of ATP synthase in mitochondria, called IF₁, conserves cellular energy when the proton-motive force collapses by inhibiting ATP hydrolysis. Around neutrality, the ...

Using electron microscopy and high-speed atomic force microscopy, researchers show the internal molecular motor behind the gliding mechanism for Mycoplasma mobile to consist of two ATP synthase-like ...

Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease. Many of these diseases are tied to a deficiency in ATP synthase thought to be triggered by ...