This new article publication from Acta Pharmaceutica Sinica B, discusses the deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for ...
National Marrow Donor Program–Sponsored Multicenter, Phase II Trial of HLA-Mismatched Unrelated Donor Bone Marrow Transplantation Using Post-Transplant Cyclophosphamide Patients were eligible for the ...
A phase I trial of a novel mTOR inhibitor AP23573 administered weekly (wkly) in patients (pts) with refractory or advanced malignancies: A pharmacokinetic (PK) and pharmacodynamic (PD) analysis No ...
Researchers in Brazil have discovered a new effect of a drug widely used as a chemotherapeutic agent and offered to patients free of charge by SUS, the national health service. Paclitaxel is ...
Table 3. Calculated Pearson and Spearman's rgcorrelation coefficients between each molecular descriptor and log Keq. The predictive equations are presented for the three sets of drugs analyzed (All ...
CCR8 is highly expressed on immunosuppressive regulatory T cells (Tregs) in various solid tumors, making it a potential target to enhance antitumor immunity and the efficacy of cancer therapies, ...
Multiple patient-derived xenograft models with prolonged complete responses associated with sustained release of the exatecan payload within the tumor over five days LONDON and PHILADELPHIA - December ...
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