NFL RedZone — an around-the-horn live highlight show demonstrating all the action on NFL Sunday — is back for Week 6 of the 2025 season.

The Arizona Cardinals face the Indianapolis Colts, led by quarterback Daniel Jones, on Sunday, Oct. 12, 2025 at Lucas Oil Stadium in Indianapolis.

The Arizona Cardinals (2-3) led the Tennessee Titans 21-6 at halftime before being outscored 16-0 in the second half.

Learn which TV channel or how to live stream the NFL Week 5 Arizona Cardinals and Tennessee Titans game, Sunday, Oct. 5.

Demercado, Murray, Michael Carter and Bam Knight combined to rush for 168 yards. That's a good sign for the Cardinals considering veteran James Conner (foot) is out for the season and backup Trey Benson (knee) will miss at least three more games.

The Saints are seeking their second consecutive victory after beating the New York Giants 26-14 in New Orleans a week ago. The Saints enter the game with a record of 1-4 while the Patriots are 3-2 following a 23-20 victory over the Buffalo Bills.

Daniel Jones connected with Tyler Warren for an eight-yard TD to give the Indianapolis Colts the lead over the Arizona Cardinals.

Daniel Jones was happy with the way the Indianapolis Colts executed in the fourth quarter to hold off the Arizona Cardinals 31-27 in Week 6.