The Tennessee Titans, led by quarterback Cam Ward, face the Arizona Cardinals, led by quarterback Kyler Murray on Sunday, Oct. 5, 2025 at State Farm Stadium in Glendale, Arizona.

The Arizona Cardinals (2-3) led the Tennessee Titans 21-6 at halftime before being outscored 16-0 in the second half.

The Arizona Cardinals continued their slide and continued to play poorly while having a lead. They lost to the Tennessee Titans 22-21 at State Farm Stadium, as Titans kicker Joey Slye made a 29-yard field goal as time expired, the third consecutive week the Cardinals have lost at the buzzer.

NFL Week 7 betting spreads, lines, point totals for every game on the NFL Week 7 schedule, with odds for favorites and underdogs in each NFL matchup.