A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.

Single-cell analyses have emerged as powerful tools for studying cellular heterogeneity and gene regulation. Single-cell chromatin accessibility sequencing (scCAS) is a key technology that enables the ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. In myelodysplastic ...

SEATTLE--(BUSINESS WIRE)--Parse Biosciences, the leader in accessible and scalable single cell sequencing, today affirmed their plans to proceed with development and future release of their Evercode™ ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

As we age, our cells age with us. Although they remain active, they become less flexible, stop dividing and sometimes respond incorrectly to signals. The reason for this lies in the cell nuclei, ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will fit into a cell’s nucleus, while the crucial parts of it remain accessible ...