Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged ...

Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers. Using a large-scale library of TC organoids they ...

Medically reviewed by Marla Anderson, MD Key Takeaways Triple-negative breast cancer is aggressive and often resists ...

Scientists from King's College London have successfully applied a new technology that disarms one of the most potent weapons cancer cells use to weaken the effects of chemotherapy drugs. Subscribe to ...

A groundbreaking cancer drug could enhance how patients respond to chemotherapy even in treatment-resistant tumours. The drug works by disarming a key defence mechanism that tumours use to protect ...

Small cell lung cancer, or SCLC, is aggressive, lethal and particularly cruel because chemotherapy initially works so well. But within just a few months, SCLC becomes resistant to drugs and dashes ...

The Smolka Lab, led by Prof. Marcus Smolka, molecular biology and genetics, recently published a study shedding light on a novel pathway that explains how cancer cells can become resistant to ...

Spiky nanorobots powered by magnets have been developed to carry drugs and pierce tumor cell membranes, a key barrier to effective cancer treatment. By boosting drug entry, these "microscopic scalpels ...