Watch the best plays from San Francisco 49ers RB Christian McCaffrey's 141-yard game against the Jacksonville Jaguars in Week ...

San Francisco 49ers running back Christian McCaffrey's best plays from his 139-yard game vs. the Los Angeles Rams during Week ...

Christian McCaffrey helped the San Francisco 49ers come out on top against the Los Angeles Rams in Week 5. Kyle Shanahan's ...

Christian McCaffrey has struggled to get going on the ground for the San Francisco 49ers. Most of that isn’t his fault. The run blocking has been average at bes ...

While the 49ers have not been productive on the ground, their running back has been producing through the air.

The San Francisco 49ers will take on the Tampa Bay Buccaneers on Sunday, and running back Christian McCaffrey isn't looking forward to it.

The SportsLine Projection Model has locked in its top Week 1 NFL anytime TD picks for players like Jahmyr Gibbs and Christian McCaffrey ...

SANTA CLARA — Mac Jones had the tough task of willing the 49ers to a 16-15 win over the Arizona Cardinals, but having Christian McCaffrey in the backfield gave the team's backup additional confidence.

San Francisco 49ers star running back Christian McCaffrey explained his savage "eliminate your feelings" mantra.

Christian McCaffrey's wife, Olivia Culpo, shared a quick get ready video ahead of the San Francisco 49ers' game on Sunday ...

Here's everything to know about Christian McCaffrey's parents, Ed and Lisa McCaffrey. Ed and Lisa married on April 4, 1992.