Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.

Classical dendritic cells (cDCs) are essential for immune responses and differentiate from hematopoietic stem cells via intermediate progenitors, such as monocyte–DC progenitors (MDPs) and common DC ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

Dr. Yasuhiro Arimura studies chromatin, the mixture of DNA and DNA-packaging proteins. Chromatin is “marked” with numerous chemical or structural cues that enable cells to organize DNA and manage how ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

Nuclear pore complexes (NPCs) govern macromolecular transport between the nucleus and cytoplasm and serve as key positional markers within the nucleus. Several protein components of yeast NPCs have ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions. Japanese researchers have revealed how changes in chromatin accessibility—how DNA ...