Indianapolis Colts guard Quenton Nelson (56) and Indianapolis Colts running back Ameer Abdullah (26) celebrate after Abdullah scores a touchdown Sunday, Oct. 5, 2025, during a game at Lucas Oil Stadium in Indianapolis. The Colts defeated the Raiders 40-6. / Christine Tannous/IndyStar / USA TODAY NETWORK via Imagn Images

With the Ravens falling apart, the Chiefs working out some kinks, and the Bills looking vulnerable, the 4-1 Colts occupy the top spot in the AFC through Week 5.

Sunday’s ugly loss gives you the feeling that if Miami loses next week, there’s nothing it can do to prevent an 0-3 start, in which case there will be talk of jobs being on the line.

Former Patriots rival Tony Dungy delivered a motivational speech to the team ahead of their 23-20 upset victory over the Bills.

Join the Indianapolis Colts in Berlin for an official watch party. Enjoy live entertainment, giveaways, and German food and beer specials.

The one silver lining for Las Vegas in the game was the play of running back Ashton Jeanty, who continued to impress as a rookie out of Boise State. “RB Ashton Jeanty has two runs of 10+ yards today – that brings his total to 12 runs of 10+ yards so far in 2025, currently tied for the most in the NFL,” reported Raiders PR on X, formerly Twitter.

The Buffalo Bills undefeated start to the 2025 season came to an end Sunday night with a 23-20 loss to the New England Patriots. The Buffalo Bills were the last remaining undefeated team in the NFL this season.

Want proof? Hours before Sunday night’s upset win over the previously undefeated Bills, one of the Patriots’ biggest rivals from the dynasty era arrived during a morning team meeting to provide some words of wisdom to a squad looking to prove something on national television.

According to Jason Fitzgerald, the Colts freed up $3.8 million in cap space by restructuring CB Kenny Moore‘s contract.  Moore, 30, wound up signing on with the Patriots as an undrafted free agent out of Valdosta State back in 2017.

How do all 32 teams in the NFL stack up against each other coming out of Week 5 of the 2025 NFL regular season? Here's an updated look from best to worst.