Every cell in the body carries essentially the same genome, yet what distinguishes a neuron from a liver cell is which genes ...

Functional genomics investigates these mechanisms from genetic variants to gene expression and regulation. We performed personalized functional... Aging and tissue repair involve heterogeneous ...

Digital DNA molecule, structure. Concept binary code human genome. DNA molecule with modified genes, 3D illustration When synthetic biologists sketch gene circuits, they usually think in terms of ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Single-nucleus RNA sequencing captures molecular changes in the prefrontal cortex across the lifespan and in health and disease.

Clearing hepatitis C sharply reduces liver cancer risk without erasing it. Across 23 studies covering 29,395 patients, HCC occurred at 1.54 per 100 person-years after sustained virologic response ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own version. Cornell researchers have discovered that DNA packaging structures ...

A fault in one of the body’s most important DNA repair genes may be quietly steering the course of several devastating blood ...

Prediction of Anthracycline Benefit in Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Early-Stage Breast Cancer by the MammaPrint 70-Gene Signature for Patients Enrolled ...

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression. Focusing ...

Targeting KDM2B or downstream protein complexes it recruits may exploit a vulnerability in high-risk medulloblastoma ...