Researchers have identified the mechanism used by the helicase ring to thread around and separate entwined DNA strands in the replication process. DNA replication is a complex process in which a ...

Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus ...

In a proof-of-concept study, scientists at Delft University of Technology in the Netherlands and the University of Illinois have successfully repurposed DNA nanopore sequencing technology to scan ...

CHAMPAIGN, Ill. – Thanks to a single-molecule imaging technique developed by a University of Illinois professor, researchers have revealed the mechanisms of an important DNA-regulating enzyme.

Enzymes, which are crucial to controlling how cells replicate in the human body, could be the very ingredient that encourages DNA to spontaneously mutate -- causing potentially permanent genetic ...

Mutated Hrq1 and Pif1 helicase enzymes shown to work together to disrupt telomere maintenance and regulation of cell division. All strands of DNA have a non-coding region at the end of the strand ...

The DNA of all organisms, be it bacteria or humans, is constantly bombarded with damage either by environmental mutagens such as the exposure to UV light or because of erroneous replication. The ...

This narrated animation illustrates the process of protein synthesis, starting with chromosomal DNA inside the cell's nucleus. A gene is transcribed into messenger RNA, which leaves the nucleus and ...