Visualizing and quantifying DNA replication dynamics in living human cells remains challenging. Here, a new super-resolution ...
A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...
In the new work, Rothemund and his colleagues used DNA origami to create a lilypad-like structure—a flat, circular surface ...
Hamilton, M. B., Pincus, E. L., Di Fiore, Anthony, and Fleischer, Robert C. 1999. "Universal linker and ligation procedures for construction of genomic DNA libraries ...
Many cellular functions in the human body are controlled by biological droplets called Liquid-Liquid Phase Separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside ...
The technique can then be used to create shapes ranging from a map of North and South America to nanoscale transistors. In the new work, Rothemund and his colleagues used DNA origami to create a ...
A time-delay circuit enables precise control over the division of synthetic DNA droplets, which mimic biological Liquid-Liquid Phase Separation (LLPS) droplets found in cells. By utilizing a ...
A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.
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