TOKYO — Doctors may eventually be able to tell whether your cells are aging prematurely without needles, blood tests, or expensive lab work. Japanese researchers have developed an experimental ...

A study in Scientific Reports evaluated a photoacoustic polydopamine-indocyanine green (PDA-ICG) nanoprobe for detecting senescent cells. Senescent cells play a role in tumor progression and ...

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

Kidney fibrosis, a common endpoint of chronic kidney disease (CKD), is strongly linked to aging, with cellular senescence emerging as a key driver in its pathogenesis. This overview synthesizes ...

Cellular senescence is commonly defined as a state characterized by permanent cell cycle arrest in the absence of cell death, in which cells have altered function. While cellular senescence has been ...

This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...