When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals are ...

Precursor cells in the embryonic neural tube are organized in a specific striped pattern which depends on the signals they receive (left). Lehr and colleagues recreated this pattern in a cell culture ...

The complex spatiotemporal signaling of human neural tube development is successfully engineered in a device using microfluidic gradients, creating a high-fidelity model of the developing human ...

In a recent article 1, we demonstrated that single morphogen gradients in the developing mouse neural tube (NT) can carry sufficient positional accuracy to explain the patterning precision of ...

Neural tube defects (NTDs) rank as the second most prevalent congenital malformation in humans, impacting the central nervous system development in approximately 1 in every 1,000 live births. Over 300 ...

Millions of neurons branch throughout our bodies, keeping them in close communication with our brains. This peripheral network begins to take shape long before birth, as the cells of a growing embryo ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

The quail is a small, unassuming bird that glides rather than flies and prefers to hide under bushes than to perch on top of a tree. And now, it’s also helping scientists understand serious birth ...

Neurodevelopment involves the brain's formation of systems responsible for learning, memory, social skills, and overall function. Critical neurodevelopmental processes such as neurogenesis, synaptic ...