A recent study uncovers how drug-resistant cancer cells induce changes in the tumor microenvironment. This phenomenon promotes cancer recurrence and explains why initially effective targeted therapies ...

Ovarian cancer treatment faces challenges with high relapse and drug resistance rates, despite initial chemotherapy effectiveness. Cytokines like IL-6 and IL-11 are associated with complex tumor ...

Starting with a study of how mutations affect sensitivity to 10 molecularly targeted drugs, researchers have laid the foundations for a prospective, systematic approach to understanding the genetic ...

Researchers at the University of Virginia have discovered a new mechanism driving drug resistance in pancreatic ductal adenocarcinoma, one of the deadliest cancers. Their groundbreaking findings could ...

All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping to uncover targets for drug development and identify potential effective ...

The company joins a group of degrader ADC (or DAC) developers that includes Bristol Myers Squibb and Pfizer.

Pathogenic bacteria have evolved a variety of mechanisms to thrive within their hosts, even in the face of antibiotic treatment. One particularly effective strategy is the expression of membrane ...

Malaria represents one of the most serious threats to human health worldwide, and preventing and curing this parasitic disease still depends predominantly on the administration of a small number of ...

Join a panel of experts in celebration of World Antimicrobial Resistance Awareness Week, that will not only raise awareness of today’s challenges, but will discuss advances in structural biology, ...