Tuberculosis is both curable and preventable, yet each year, it still kills more people than any other infectious disease. One reason is that current treatments hinge on rifampicin, an antibiotic that ...

For 2007, the WHO estimated 511,000 cases of multidrug-resistant (MDR)-TB, representing approximately 5% of all TB cases worldwide. Extensively drug-resistant (XDR-TB) strains have been detected in at ...

African scientists have developed a nanoscale drug delivery system to treat pericarditis, a drug-resistant and lethal tuberculosis (TB). The scientists' system can breach the heart's protective ...

Tuberculosis (TB) is the world's biggest infectious disease killer with multidrug-resistant TB (MDR-TB) posing a particular threat to global health. A study shows that resistance to the new MDR-TB ...

Sydney researchers have found that Levofloxacin substantially reduces risk of drug-resistant tuberculosis. This discovery offers new hope against a disease that infects more than 400,000 people ...

Tuberculosis (TB) remains a global health challenge, affecting millions each year. In 2023, an estimated 10.8 million people contracted TB, with 1.25 million deaths, according to the World Health ...

Researchers found that pairing the antibiotic rifampicin with a second compound turned multidrug resistance into a weakness—providing proof of concept for using basic science to design life-saving ...

The novel antibiotic candidate sorfequiline has the potential to shorten and improve tuberculosis (TB) treatment when combined with pretomanid and linezolid (SPaL), according to new clinical trial ...

Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs, while others may warrant more aggressive therapy, according to the findings of a new ...

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Before the successful Nix-TB trial, which took place in South Africa from 2015 to 2017, patients with extensively drug-resistant TB (XDR-TB) had to follow a complicated treatment plan for the ...

Suggested Citation: "2 The Global Spread of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis." Institute of Medicine. 2009. Addressing the Threat of Drug-Resistant Tuberculosis: A ...