In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival, revealing a potential strategy for selectively targeting tumours associated with ...

An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment ...

Dihydropteroate synthase (DHPS) is a crucial enzyme in the folate biosynthetic pathway, catalysing the formation of essential folate cofactors that underpin DNA synthesis and cellular functioning.

Leukemia is notorious for being very aggressive and hard to eradicate from the body. The culprits are leukemic stem cells—known as “seed” cells—that drive resistance to chemotherapy and can trigger a ...

Renin–angiotensin system (RAS) inhibitors — including angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) — slow the progression of mild or moderate chronic kidney ...

Researchers have found a small molecule enzyme inhibitor capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases. Researchers at the University of ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University ...

In efforts to better understand how plant photosynthesis is regulated, scientists are studying how Rubisco activity responds ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

The proceeds will support the advancement of STC-15 in a Phase 2 study in select sarcoma indicationsFirst‑in‑class METTL3 inhibitor reprograms ...