When profiling blood samples by RNA-sequencing (RNA-seq), RNA from haemoglobin (Hgb) can account for up to 70% of the transcriptome. Due to considerations of sequencing depth and power to detect ...

Functional genomics investigates these mechanisms from genetic variants to gene expression and regulation. We performed personalized functional... Aging and tissue repair involve heterogeneous ...

Clearing hepatitis C sharply reduces liver cancer risk without erasing it. Across 23 studies covering 29,395 patients, HCC occurred at 1.54 per 100 person-years after sustained virologic response ...

Bladder cancer remains one of the most common and deadly malignancies worldwide, and researchers continue to hunt for ...

Researchers have developed 'tomoseqr' -- a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free to use and has been ...

Researchers at University of Tsukuba have developed "tomoseqr"—a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free ...

Dengue virus infects an estimated 390 million people each year, and roughly 96 million of them develop clinical or ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Researchers at the Yale School of Public Health have discovered the evolutionary rhythm of gene expression, showing that changes happen at strikingly varied rates. In the study, published in Molecular ...

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they ...