Researchers discover that glycogen and N-linked glycans accumulate in fibrotic regions of the lung and may be important for therapy development. Ramon Sun, a biochemist at the University of Florida ...

Glycogen, a hyperbranched polymer of glucose, plays a central role as an energy reserve across diverse organisms. In Escherichia coli, its biosynthesis is linked not only to energy storage but also to ...

Phosphatidylinositol 3-kinases (PI3Ks) are a family of enzymes that catalyze the phosphorylation of phosphatidylinositol at the D-3 position of the inositol ring, serving critical functions in ...

BACKGROUND: PYGM (muscle glycogen phosphorylase), the rate-limiting enzyme in glycogenolysis, plays an indispensable role in maintaining cardiac energy metabolism. However, the role of PYGM in the ...

Type 2 diabetes (T2D) has become one of the leading chronic diseases worldwide in terms of both incidence and mortality. According to the International Diabetes Federation (IDF), approximately 537 ...