Heparin is frequently employed to mitigate the risk of clot formation in the leg veins following surgery, to treat venous thromboses and to prevent thrombotic occlusions of arteries in patients at ...

Please provide your email address to receive an email when new articles are posted on . A phase 1A study consisted of a single ascending dose portion and a multiple ascending dose portion designed to ...

VLX-1005 is a first-in-class and selective small molecule inhibitor of 12-lipoxygenase, a key target within the arachidonic acid pathway. The Food and Drug Administration (FDA) has granted Orphan Drug ...

Credit: Getty Images. VLX-1005 is a first-in-class, selective small molecule inhibitor of 12-lipoxygenase, a key target within the arachidonic acid pathway. The Food and Drug Administration (FDA) has ...

Heparin-induced thrombocytopenia (HIT) is a clinically significant immune-mediated adverse reaction to heparin therapy. It is typified by a reduction in circulating platelets while paradoxically ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Spontaneous heparin-induced thrombocytopenia is a pro-thrombotic syndrome in which anti-heparin antibodies ...

A team of researchers developed 3 quality improvement measures embedded in electronic health records (EHRs) to improve care delivery in patients with heparin-induced thrombocytopenia. HIT is known as ...

Purpose: A case of heparin-induced thrombocytopenia (HIT) complicated by warfarin-induced skin necrosis (WISN) is reported. Summary: A patient with a history of hypertension, heart failure, and ...

Development program for VLX-1005, a novel small molecule 12-LOX inhibitor, awarded Fast Track designation by US Food and Drug Administration FREDERICK, Md., June 13, 2022 /PRNewswire/ -- Veralox ...

The use of heparin is associated with a risk for HIT regardless of the route of administration or dose. Argatroban and lepirudin are FDA-approved for the treatment of HIT. While both agents have been ...

Heparin is widely used as an anticoagulant, but evokes in some patients a potentially life-threatening condition called HIT. Clinical scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have ...