The first antihistamine that the Food and Drug Administration approved was diphenhydramine. The compound was created in 1943, and the Parke-Davis pharmaceutical company brought it to market in 1946 ...
Benadryl (diphenhydramine) is an over-the-counter (OTC) antihistamine that is commonly used to treat allergy symptoms, like sneezing, itching, and hives (rashes), motion sickness, and even difficulty ...