To evaluate the safety of sequentially administered recombinant (r) human (h) interleukin-12 (IL-12) and interferon alfa-2b (IFN-α-2b) in patients with advanced cancer and to determine the effects of ...

Purpose: To maintain interferon gamma (IFNγ) induction by recombinant human interleukin-12 (rhIL-12) and enhance its activity against melanoma and renal cell cancer, a regimen of twice-weekly ...

Autoantibodies against interleukin-12 (anti–interleukin-12) are often identified in patients with thymoma, but opportunistic infections develop in only some of these patients. Interleukin-12 (with ...

An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice ...

During the COVID-19 pandemic, mRNA vaccines came to the rescue, developed in record time and saving lives worldwide. Researchers in the Precision Vaccines Program at Boston Children's Hospital have ...