In order to evaluate the advantages and disadvantages of each technique at different stages of disease, we performed a study analyzing CML cases in parallel with chromosome analysis (CA), ...

There is an increasing demand for comprehensive genome analyses of single cells. In cancer genetics, single-cell approaches allow monitoring minimal residual disease or the assessment of heterogeneity ...

Anaplastic large-cell lymphoma: clinical and prognostic evaluation of 90 adult patients. When to harvest peripheral-blood stem cells after mobilization therapy: prediction of CD34-positive cell yield ...

FISH provides a useful adjunct to cytogenetic analysis, its main advantage being that it does not rely on dividing cells and can therefore be performed on cells in interphase. Blood can be used if ...

CONCLUSION: For patients with MM who were treated with conventional-dose chemotherapy, interphase FISH for 13q14, 17p13, and 11q provides prognostically relevant information in addition to that ...