Figure 1. Mechanism of biotin interference with immunoassay methodologies. Immunoassays in this case report contain a solid phase with a wash step that physically separates the label-bound ...

The term biotinylation refers to the process of binding biotin to either a protein or a nucleic acid, or in some cases to another type of molecule. An antibody is one of these potential targets, a ...

Recent research by Rafael C. Bernardi at the University of Illinois, Urbana-Champaign examines why a common tool in biotechnology -- the binding of streptavidin to biotin -- shows different mechanical ...

Biotin can amplify signals by forming complexes of large size with avidin or streptavidin. There are several techniques that use biotinylated secondary antibodies for this purpose, which are dealt ...

A new ultrabright fluorescent label might make bioassays faster and more sensitive. Srikanth Singamaneni and coworkers at Washington University in St. Louis make their “plasmonic-fluor” labels of a ...