Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization and protein components of a lipid-transfer complex known as LPD-3.

Oxidized lipids—fats structurally altered by enzymes, oxygen or free radicals—are double-edged swords that can both quell and ignite systemic inflammation, according to a new comprehensive review ...

A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines ...

Structural, functional and computational evidence demonstrates that when certain ion channels are activated by mechanical force, they assume an open configuration in which the pore is formed by both ...

Scientists have uncovered a hidden layer of organization in the brain by creating the first detailed 3D map of its lipids, ...

It has been discovered that the chain length of lipids that make up cell membranes increases with age, a phenomenon common to mice, nematodes, fruit flies, and humans. It has also been confirmed that ...

Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic diseases such as obesity and diabetes. In addition, it plays a critical role ...

An AI-identified lipid called P1 delivered mRNA 14.8 times more efficiently than the clinically approved lipid ALC-0315. Lipid P1's unique three-dimensional conformation allows it to bind ...

High-resolution mass-spectrometry imaging mapped distinct lipid distributions across the tegument, intestine, ovary and ...

“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...

A new review details how liposomes, cubosomes, and solid lipid nanoparticles are overcoming the eye's formidable barriers to ...