Over the last decade, poisonings and deaths linked to the use of local anesthetics have decreased. Even so, poisonings from ...

The American Society of Regional Anesthesia and Pain Medicine has published a practice advisory on local anesthetic systemic toxicity (LAST) called “Guidelines for the Management of Severe Local ...

Our results suggest that ultrasound guidance, HBV infection and the female sex are risk factors of LAST in LPBs and SNBs. For patients infected with HBV or female patients undergoing LPBs and SNBs, ...

One lot of Lidocaine HCl Topical Solution 4%, 50ml has been recalled by Teligent Pharma after company-testing found it to be super potent. As the Teligent-written, FDA-posted recall notice states, ...

For the second time in just over six weeks, Teligent Pharma recalled Lidocaine HCl Topical Solution 4%, 50ml for super potency. This time, instead of just one lot, Teligent pulled five lots, four ...

Teligent Pharma has voluntarily recalled two lots of Lidocaine HCl Topical Solution USP 4% because testing found it to be “super potent.” People could be using a higher than intended dose of the ...

All current local anesthetics block sensory signals—pain—but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor from ...

Inspired by the natural bonding between a class of potent local anesthetics called site-1 sodium channel blockers (S1SCBs) and peptide sequences on the sodium channel in the nerve cell membrane, ...

A New Jersey pharmaceutical company is recalling some lots of its lidocaine hydrochloride topical solution because it may be “super potent.” According to an announcement with the U.S. Food and Drug ...