There have been many advancements in the treatment and diagnosis of lupus. With proper care and a healthy lifestyle many people with lupus can live a normal life. When lupus is fatal, it’s usually due ...

Objective Macrophages and kidney cell pyroptosis/ferroptosis could play an important role in the pathogenesis of lupus ...

From 1999-2020, systemic lupus erythematosus (SLE)-related mortality rates consistently declined across demographic groups. Rates remain disproportionately high among Black and female patients. The ...

Please provide your email address to receive an email when new articles are posted on . Despite declining mortality rates, racial, sex and geographic disparities persist for patients with lupus. Early ...

Kezar Life Sciences went all in on its autoimmune candidate zetomipzomib after a restructuring last year. Now, the company has hit the brakes on its phase 2b study of the drug in lupus nephritis ...

Please provide your email address to receive an email when new articles are posted on . Kezar Life Sciences has paused a phase 2b trial of zetomipzomib in active lupus nephritis after reporting four ...

The FDA has placed Kezar Life Sciences’ lupus trial on hold after the biotech flagged four deaths during the phase 2b study. Kezar had been evaluating the selective immunoproteasome inhibitor ...