University of Pennsylvania Perelman School of Medicine and Yale University School of Medicine, along with other collaborators ...

In recent years, cancer researchers have made major breakthroughs by using the body's immune system to fight cancer. One of ...

UVA researcher Blandine Baffert, working in the lab of UVA Health’s Sanja Arandjelovic and collaborating with researchers in ...

Tumors in the human body contain immune cells called macrophages that are naturally capable of attacking cancer. However, ...

Macrophages serve as the Swiss army knives of the innate immune system, switching between phenotypes to perform different functions in response to the surrounding environment. One of their key ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Metastasis, or cancer spreading, is complex and still largely mysterious. As a tumor grows, it interacts constantly with the surrounding environment, including blood vessels, signaling molecules, and ...

Daniele Canzio, PhD, of the Department of Neurology and Balyn Zaro, PhD, of the Department of Pharmaceutical Chemistry have ...

Researchers have identified an enzyme that controls the maturation and long-term survival of tissue-resident macrophages.

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.