Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their structures in a natural membrane environment is crucial for enhancing our ...

In a pioneering discovery, researchers at UNIST have captured, for the first time, the elusive intermediate stages involved in the pairing of cell membrane proteins. Contrary to long-held beliefs that ...

EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily enhances ...

A research team at Leipzig University has identified a mechanism in adhesion G protein-coupled receptors (adhesion GPCRs), a ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

Researchers have developed a new artificial intelligence (AI) model that can more accurately predict how proteins interact ...

Membrane proteins are the gateway to cells and are involved in many critical functions. Each membrane protein is unique, and their complexity makes it difficult to fit into a standardized expression ...

Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...

Viruses are masters at invading our cells thanks to specialized proteins that coat their surfaces. When scientists design ...

Draupnir’s novel SORTAC platform expands reach of targeted protein degradation to extracellular proteins, demonstrating in vitro and in vivo efficacy against difficult-to-drug targetsStudy further ...