Week 6 of the NFL season is finally here, and once again injuries are a major storyline -- especially after several important players suffered injuries in Week 5 that could affect this week and even the remainder of the season.

NFL RedZone — an around-the-horn live highlight show demonstrating all the action on NFL Sunday — is back for Week 5 of the 2025 season.

In Week 5, nine underdogs covered in 14 games and every one of our NFL experts finished with a record above .500.

SportsLine's computer simulation model has locked in a $10 5-leg NFL Week 6 parlay that pays well over $44,000

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