Autoimmune diseases are the molecular equivalent of "friendly fire": the body attacks itself instead of harmful invaders. Now, researchers from Japan have found that interrupting the complex interplay ...

Researchers have found that repulsive guidance molecule-a (RGMa) induces macrophages to recruit neutrophils to nerve lesions in neuromyelitis optica, where they kill off astrocytes, causing pain and ...

The early diagnosis and treatment of neuromyelitis optica (NMO) generally improve the outlook for people with this condition. Corticosteroids and immunotherapy are the main treatment options. NMO, ...

The autoimmune condition neuromyelitis optica (NMO) may affect the optic nerve, spinal cord, and brain. Life expectancy varies based on a person’s age, race, disabilities caused by NMO, and rate of ...

Neuromyelitis optica is a rare chronic condition that causes eye pain and even vision loss. This disease happens when your own immune system attacks your nervous system. In this article, we look at ...

A monoclonal antibody (mAb) against a glycoprotein called repulsive guidance molecule-a (RGMa) may provide an efficient therapeutic strategy for treating neuromyelitis optica (NMO), scientists at ...

Neuromyelitis optica (NMO) is a chronic health condition that affects nerves in the eyes, spinal cord, and sometimes brain. It’s also known as Devic disease or Devic syndrome. It may cause vision loss ...

Neuromyelitis optica spectrum disorder (NMOSD) is neuroinflammatory disease characterized by optic neuritis and myelitis with presence of anti-aquaporin-4 (AQP4) antibodies. Satralizumab is an anti-IL ...

"Our study showed that changes in thalamic volume correlates with fatigue severity. To the best of our knowledge, this study is the first to identify the MRI substrate of fatigue in patients with ...