Broad-spectrum antibiotics will alter the composition of the human gut microbiome, with transiently reduced bacterial diversity. Thus, it is reasonable to hypothesize that antibiotic-induced ...
Investigating the relationship between IL-1 and inflammation in inflammatory bowel disease (IBD), researchers unveiled mesenchyme homeobox 1 (MEOX1), an IL-1-dependent transcription factor that is ...
Associate Professor of Medicine, Pritzker School of Medicine, Chicago, Illinois; Assistant Professor of Medicine, Section of Gastroenterology and Nutrition, Department of Medicine, University of ...
Inflammatory bowel disease (IBD) encompasses a spectrum of disorders characterized by chronic inflammation of the digestive tract, driven in part by a dysregulated immune response to the gut ...
mTOR, mammalian target of rapamycin; p70S6K, The 70kDa ribosomal S6 kinase 1; NLRP3, NOD-like receptor thermal protein domain associated protein 3; ASC, apoptosis-associated speck-like protein ...
In a study published in Nature Immunology on January 6, a research team led by Prof. QIAN Youcun from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences ...
Inflammatory bowel disease (IBD) is sometimes associated with spondyloarthritis (SpA) and it highly impacts patients’ quality of life. It is crucial to understand the pro-inflammatory processes that ...
Please provide your email address to receive an email when new articles are posted on . TL1A inhibitors have shown both anti-inflammatory and anti-fibrotic activity in IBD. This class of drugs offers ...