Pore-forming toxins are common bacterial poisons. They attack organisms by introducing holes in cell membranes. A team of scientists at the Technical University of Munich (TUM) has now unraveled the ...

Future Microbiol. 2013;8(1):73-84. Work in the Mulvey laboratory is supported by NIH grants AI095647, AI090369 and AI088086. TJ Wiles was funded by NIH Genetics Training Grant T32-GM007464. The ...

Pore-forming toxins (PFTs) are a diverse class of proteins capable of disrupting cell membranes through the formation of transmembrane channels. These molecular machines play a central role in both ...

Pore-forming toxins are common bacterial poisons. They attack organisms by opening holes in cell membranes. A team of scientists at the Technical University of Munich (TUM) has now unraveled the ...

Get unlimited access to ad-free articles and exclusive content. Discovery News Bacteria are becoming more resistant to the best weapon we have against them: antibiotics. But what if we could live ...

Six years ago, researchers described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis. However, the mechanism for its secretion from the bacterium was unknown. Now, ...

Blocking calcium entry or the MAPK relay was enough to stop every downstream response. Breathing in the duo drives classic allergy signs in mice, with eosinophils in the lungs, T-helper-2 cells, and ...