The last two decades have witnessed the steady growth of the protein drug market. As original recombinant products come off patent, generics/ biosimilars are also beginning to be manufactured. The ...

Reverse phase protein array is a high-throughput technology that performs protein assays on thousands of samples simultaneously, including tissue and cell lysates, serum, plasma or other body fluids.

Reverse phase protein array (RPPA) is a high-throughput technology that performs protein assays on thousands of samples simultaneously, including tissue and cell lysates, serum, plasma or other body ...

As gene therapies continue to advance, the demand for scalable, reproducible, and efficient potency assays is rapidly increasing—especially for adeno-associated virus (AAV) vectors. Accurate ...

This poster was originally authored by John Vincent, Matthew Burnham, Gerrit Daubner, and Martin Main of the Medicines Discovery Catapult. It was presented at ELRIG Drug Discovery 2023. Methods to ...

Targeted protein degradation (TPD) is a promising alternative to conventional small-molecule drugs. Rather than inhibiting a single enzyme’s function, degrader molecules label selected ...

As part of the immune response, inflammation plays a vital role in the host defense and is dictated by the balance between stimulatory and inhibitory mediators. Inappropriate regulation of ...

This article examines the key differences between primary and secondary screening in drug discovery, detailing how primary ...

(Nanowerk Spotlight) Metal-organic frameworks (MOFs) have emerged in recent years as an exciting new class of materials with tremendous potential in diverse fields such as gas storage, drug delivery, ...

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...