In a study published in Nature Methods, a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous ...
Swedish chemist Jöns Jacob Berzelius, in a letter to a fellow chemist, first suggested the name ‘proteins’ for a particular class of biological substances, deriving it from the Greek word proteios, ...
In drug discovery, virtual screening is a fast and cost-effective way of narrowing down vast chemical libraries to identify the most promising hits, reducing synthesis and testing requirements while ...
Under the foundation of research cooperation established through the Ministry of Science and ICT's InnoCORE (InnoCORE) project, KAIST InnoCORE researchers have derived meaningful research results.
We used immunohistochemistry to assess 124 NEC tumor samples from any primary site for DLL3 and 53 for SEZ6 and defined positivity as ≥1% staining. We describe the landscape of DLL3 and SEZ6 ...
Professor Gyu Rie Lee of the Department of Biological Sciences successfully designed artificial proteins that selectively ...
Biochemical hits often fail in cells. In this interview, Dr. Phil Hargreaves explores how cellular target engagement methods ...
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...