Protein translocation across cellular membranes is fundamental to both prokaryotic and eukaryotic life, directing nascent polypeptides into organelles, the periplasmic space or the extracellular ...
These images captured using high-speed atomic force microscopy, represent the snapshots of the protein substrate getting translocated through the SecYEG-SecA complex. The left image indicates the ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
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