Accurate DNA replication is essential for genome maintenance. Two recent reports have uncovered new molecular mechanisms controlling the termination phase of DNA replication in higher eukaryotes and ...
What happens to DNA replication when its components compete with other processes for access to the genome? Purified surface immobilized single GFP molecules on a slide (1). DNA replication is often ...
DNA replication is essential to all life, yet many basic mechanisms in that process remain unknown to scientists. The structure of the replisome--a block of proteins responsible for unwinding the DNA ...
Single-molecule imaging techniques have enabled researchers to reveal the workings of the replisome, the molecular machinery that replicates DNA. A team including researchers from the University of ...
Scientists look at the base pairs that compose the "rungs" of the DNA ladder to determine a genome's sequence. The success of E. coli bacteria depends on their ability to multiply very rapidly by ...
These cartoons show the old "textbook" view of the replisome, left, and the new view, right, revealed by electron micrograph images in the current study. Prior to this study, scientists believed the ...
The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from physicists is ...
Reactive oxygen species (ROS) were long regarded as harmful by-products of mitochondrial metabolism, but growing evidence—including our own—shows that ROS also signal to core processes such as ...
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