Understanding human biology requires more than mapping our genes—we must also understand how gene expression is regulated to guide healthy development, growth, and maintenance of our body systems over ...

Scientists have revealed the DNA sequence code of the “initiator,” a crucial sequence that kick-starts gene activation. A machine learning analysis of a half million experimental data points yielded ...

In a scientific feat that broadens our knowledge of genetic changes that shape brain development or lead to psychiatric disorders, a team of researchers combined high-throughput experiments and ...

In disease research, it's important to know gene expression and where in a tissue the expression is happening, but marrying the two sets of information can be challenging. "Single-cell technologies, ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

When two homozygous plant lines with different characteristics are crossed, the resulting offspring are often more robust and productive than their parents. This phenomenon is called heterosis. It can ...

Precise activation of tens of thousands of genes is critical for healthy development and growth. Specialized segments of our DNA are responsible for carefully orchestrating genetic sequences that ...

The study is part of the PsychENCODE Consortium, which brings together multidisciplinary teams to generate large-scale gene expression and regulatory data from human brains across several major ...