One of the main challenges for tuberculosis (TB) therapy is how to deliver drugs to the site of disease. Once the body’s immune system is infected with tuberculosis, it forms granulomas—tight clusters ...

BIRMINGHAM, Ala. – For 70 years, clinicians thought they knew the shape of tuberculosis granulomas in the lungs of patients. Histology — the study of microscopic structures in thin slices of lung ...

A study has identified a combination of medications that may improve blood flow within granulomas, benefiting drug delivery. The study leverages decades of cancer research to study ...

When the cells clump together, they protect the body from potential threats in two ways. The first is keeping an infection in one place to stop it from spreading to other parts of the body. The second ...

MicroCT of infected human lung tissue, along with histology and immunohistochemistry, was used to construct images of TB granulomas, airways and vasculature. For 70 years, clinicians thought they knew ...