Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...

There are only about 20,000 different genes in the human genome, yet our bodies are filled with an incredible diversity of cell types performing innumerable functions. The key to that diversity in ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell ...

Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...

Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the ...

Viruses are entities that have to infect other cells in order to replicate. They may have genomes that are made of DNA or RNA. We are still discovering new types of RNA viruses, as shown in two new ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--CAMP4 Therapeutics, a biotechnology company harnessing the power of regulatory RNA to restore healthy gene expression, announced research published by the lab of ...

Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early-onset form of diabetes. Smaller-scale mutations in the very same gene are also common and quietly nudge millions of people ...

Our bodies’ molecular machinery breaks down with age. DNA accumulates mutations. The protective ends of chromosomes erode away. Mitochondria, the cell’s energy factory, falter and break down. The ...

BACKGROUND: Alternative splicing plays crucial roles in normal heart development and cardiac disease by influencing protein-coding sequences, functional domains, and molecular networks. However, a ...