A grape-like structure in the brain called the choroid plexus becomes enlarged and shows increased accumulation of abnormal inflammatory molecular signaling in people with Alzheimer's disease, ...
In the “omics” era, where bigger is better, the Global Neurodegeneration Proteomics Consortium is making a splash. To date, this two-year-old initiative led by Gates Ventures and Johnson & Johnson has ...
Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...
The brain is among the most “immune-privileged” of organs primarily through the highly selective permeability of the blood-brain-barrier (BBB), its minimal lymphatic drainage, the presence of ...
In 37 people with post-COVID neuropsychiatric conditions -- most commonly, brain fog -- there was no evidence of abnormal cytokines in cerebrospinal fluid (CSF) or blood-brain barrier dysfunction, ...
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from ...