BOTTOM LINE: The Philadelphia Phillies play the Boston Red Sox with a 1-0 series lead. Philadelphia is 57-43 overall and 32-18 at home. The Phillies have a 37-8 record in games when they out-hit their opponents. Boston has gone 22-28 in road games and 54-48 overall. The Red Sox have a 25-8 record in games when they hit at least two home runs.

The Boston Red Sox lost in a truly unique fashion Monday night, losing to the Philadelphia Phillies on a walk-off catcher's interference call in 10 innings.

SportsLine's model simulated Boston Red Sox vs. Philadelphia Phillies 10,000 times and revealed its MLB picks for Monday's matchup at Citizens Bank Park in Philadelphia

The Boston Red Sox (54-49) and Philadelphia Phillies (58-43) tussle in the Wednesday finale of a 3-game interleague series. The first pitch from Citizens Bank Park is slated for 7:05 p.m. ET (ESPN). Let's analyze BetMGM Sportsbook's MLB odds around the Red Sox vs. Phillies odds and make our expert MLB picks and predictions for the best bets.

It’s Wednesday, July 23 and the Red Sox (54-49) are in Philadelphia to take on the Phillies (58-43). Lucas Giolito is slated to take the mound for Boston against Jesús Luzardo for Philadelphia. The Phillies held the Red Sox to one run and held onto a 4-1 victory to follow up the 3-2 win in extra innings on Monday.

Philadelphia looks to complete the sweep against Boston with Luzardo facing Giolito in tonight's nationally televised matchup at Citizens Bank Park.

The Red Sox look to bounce back from back-to-back losses to open the series, as the Phillies attempt to go for the sweep on Wednesday.