A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the ...

Tuberculosis is the world's leading infectious cause of death, killing more than one million people each year. When the antibiotic bedaquiline was introduced in 2012, it was the first new ...

According to other leading TB researchers, these new findings from Gerratana and her colleagues will be extremely valuable for the design of structure-based inhibitors specific for M. tuberculosis ...

Tuberculosis, a bacterial infection which generally affects the lungs, is a global threat; worldwide, ... Citation: Scientists break down tuberculosis structure (2018 ...

Scientists have paved the way for the development of new drug therapies to combat active and asymptomatic (latent) tuberculosis infections by characterizing the unique structure and mechanism of ...

Tuberculosis (TB) bacteria infect a third of the world's population and the disease kills 1.8 million people annually. ... Structure of tuberculosis drug target determined ...

This bacterial structure explains why TB can withstand harsh environmental conditions and resist many standard antibiotics. ... However, not everyone exposed to TB bacteria develops the disease.

Scientists have determined the detailed structure of a bacterial protein complex critical for tuberculosis infection. This knowledge could aid the development of therapeutics and vaccines. ... TB ...

With drug-resistant tuberculosis on rise worldwide, scientists are racing to develop new vaccines and other treatments to combat the deadly bacterium, which lays dormant in about a third of the ...

Tuberculosis fights off the toxic agents, acidity and oxidants, that our immune system sends to destroy it, which is why the maddeningly drug-resistant bacterium can survive in harsh conditions in ...

The tuberculosis bacterium has all the genes required to produce vitamin B12 but, ... The structure revealed a major surprise: a water-filled cavity that spans the entire cell membrane, ...