The paper contains a description of the extent to which the use of randomization in experimental designs permits evaluation of the experimental results. The case considered is that in which the whole ...

When subjects choose their own treatment (are self-selected into treatments based on their varying compliance with assignment to treatment states), many of the well-developed techniques of ...

Outcome-adaptive randomization is one of the possible elements of an adaptive trial design in which the ratio of patients randomly assigned to the experimental treatment arm versus the control ...

The genetic and clinical heterogeneity of breast cancer makes the identification of effective therapies challenging. We designed I-SPY 2, a phase 2, multicenter, adaptively randomized trial to screen ...

Sound experimental design is of vital importance when conducting any scientific experiment. Choices made at the design stage have the potential to drastically impact the results of any study. A strong ...

Introductory quantitative skills required to conduct experimental research and analyze resulting data. Principles of measurement, modeling of experimental data, and statistical design of experiments.

Methods for designing and analyzing industrial experiments. Blocking; randomization; multiple regression; factorial and fractional factorial experiments; response surface methodology; Taguchi’s robust ...