The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...

BACKGROUND: Right ventricular failure drives both morbidity and mortality in pulmonary arterial hypertension (PAH), but the mechanism of transition from compensated right ventricle (cRV) to ...

Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality globally. Low-density lipoprotein cholesterol is a causal risk factor for atherosclerotic cardiovascular ...

BACKGROUND: Consensus-based clinical practice guidelines recommend echocardiographic surveillance intervals based on aortic stenosis (AS) severity; however, real-world surveillance practices and ...

Circulation: Population Health and Outcomes, a journal of the American Heart Association, invites applications for an Associate Editor to join the journal’s new editorial team led by incoming ...

BACKGROUND: There is limited evidence of the relationship between aortic and iliac calcification and aortic events (aortic dissection or aneurysm rupture) and major adverse limb events (MALEs; ...

In the article by Redd et al, “Therapeutic Inhibition of Acid Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury,” which published online on July 15, 2021, and appears in ...

Immune checkpoint inhibitors (ICIs) have transformed oncology care by unleashing T-cells to achieve antitumor effects but can cause inflammatory adverse events including myocarditis. 1 ICI-myocarditis ...

You have been diagnosed with heart failure, but you are not alone. There are now more than 5 million Americans living with heart failure. Fortunately, with advances in treatment, you may live longer ...

Several studies have shown the safety of MRI after coronary stenting; however, few of them included patients soon after stenting. In this report, we describe a case of MRI-induced stent dislodgment ...

This clinic has been using the PULS Cardiac Test (Predictive Health Diagnostics Co., Irvine, CA) a clinically utilized measurement of multiple protein biomarkers, which generates a score predicting ...