Basic research, often termed fundamental, frontier, blue-sky, curiosity-driven—or even useless—is the pursuit of knowledge ...

Several recent studies show that the E3 ligase RNF114 recognises a hybrid ADP-ribose-ubiquitin modification on substrate ...

Previous studies have already established AP’s ability to arrest liver-stage development in the rodent malaria model, P.

Understanding temporal dynamics in tissue biology is key to linking transcriptomic snapshots to physiological function.

This cover highlights the article Programmed cell revival from imminent cell death enhances tissue repair and regeneration by ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. DNA i-motif structures are formed in the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Plasma membrane repair is a fundamental ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. ABCB1 is a broad-spectrum efflux pump central ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Autophagy is responsible for clearance of an ...

Many compounds being considered as candidates for advanced biofuels are toxic to microorganisms. This introduces an undesirable trade‐off when engineering metabolic pathways for biofuel production ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. It remained unknown how the ubiquitin ligase ...

Current understandings on cell motility and directionality rely heavily on accumulated investigations of the adhesion–actin cytoskeleton–actomyosin contractility cycles, while microtubules have been ...