In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning ...
In many species, introduction of double-stranded RNA (dsRNA) induces potent and specific gene silencing, a phenomenon called RNA interference or RNAi. The apparently widespread nature of RNAi in ...
Small interfering RNAs (siRNAs) and short hairpin RNAs (shRNAs) serve as the effector molecules of RNA interference (RNAi). Important mechanistic advances have recently been made in understanding the ...
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